BDBM50207145 CHEMBL3946995::US9550741, I-1
SMILES O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1ccco1
InChI Key InChIKey=AAELEHAFAYIZRH-WGSAOQKQSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50207145
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
US Patent
Shanghai Institute of Pharmaceutical Industry
US Patent
Affinity DataKi: 1.30nMpH: 7.4Assay Description:1. Experimental Materials:The isotopic ligand of 5-H1A receptor [3H]0.8-OH-DPAT (purchased from PE Corporation), (+)5-hydroxytryptamine (purchased fr...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
US Patent
Shanghai Institute of Pharmaceutical Industry
US Patent
Affinity DataKi: 1.30nMpH: 7.4Assay Description:1. Experimental Materials:The isotopic ligand of 5-H1A receptor [3H]0.8-OH-DPAT (purchased from PE Corporation), (+)5-hydroxytryptamine (purchased fr...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
US Patent
Shanghai Institute of Pharmaceutical Industry
US Patent
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HEK293 cell membranes after 60 mins by scintillation counting metho...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
US Patent
Shanghai Institute of Pharmaceutical Industry
US Patent
Affinity DataIC50: 46nMAssay Description:Antagonistic activity at 5-HT1A receptor (unknown origin) expressed in CHOK1 cells co-expressing G-alpha 15 assessed as inhibition of serotonin-induc...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
US Patent
Shanghai Institute of Pharmaceutical Industry
US Patent
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at 5-HT1A receptor (unknown origin) expressed in CHOK1 cells co-expressing G-alpha 15 by Fluo-4 dye based FLIPR assayMore data for this Ligand-Target Pair